This video shows that's it's possible to run multiple instances of the Lync 2010 client.
I am running natively, so I am not using ThinApp or App-V.
I will follow this up later with a how-to blog.
Running Multiple Instances of Lync 2010
RW
> written by
Remko Weijnen
I work on Windows internals, application delivery, security, reverse engineering, automation and AI — building tools, debugging strange behaviour and taking systems apart to understand how they work.
So how did you manage it mate?